Episode 20: Welcome to the MCAT Podcast series, where Doctor Dan will cover the actual science material required for the MCAT. Starting off with an overview of Biological Sciences topics, we’ll get increasingly more specific as time passes. [display... read more
  Aliases Solubility Working Form Functions Deficiency Toxicity Vit A Carotene, Retinol Fat cis-retinol, trans-retinol, retinoic acid, carotene Vision, transcription regulation, antioxidant Vision problems, oxidative damage Yes (retinol); No (carotene... read more
 Enzymes Subject to Phosphorylation  Ca++ and cAMP are intracellular 2nd messengers that respond to hormones binding cell surface receptors When adenylate cyclase is stimulated, intracellular cAMP levels are elevated (made from ATP)  All protein pho... read more
HYDROLASES:Â CLEAVES MOLECULES USING HYDROLYSIS Â Esterases: a hydrolase that hydrolyzes an ester into its components: an alcohol & an acid. Â Acetycholine esterase [nerve gas blocks] Phosphodiesterase 93,104, Cholesterol esterase 30 Â Lipases: a ... read more
Transport Mechanisms  Ca++ efflux from ventricular myocardial cells during diastole – secondary active (Na+ coupled)  Ca++ uptake by sarcoplasmic reticulum – primary active  Ca++ uptake by terminal varicosities of sympathetic nerve endin... read more
Sickle Cell Anemia (Hb S disease) – Results when a glutamate is replaced by valine at position 6 of the b globin chain. Symptoms include anoxia, poor circulation, and crises when variables that lower oxygen affinity (i.e. ÂBPG, ¯pH, etc) a... read more
 Essential Amino Acids Lys, ISO, LEU, THR, VAL, TRY, PHE, MET, HIS, ARG Required in diet; no exception “Little TV Tonight (PM) – HA”  Nonessentials Serine → Gly or Cys (from Homocysteine + Ser) Glutamate → Gln, Pro, Arg     Â... read more