Episode 33: Listen to this science content review and learn its format for your own audio notes. [display_podcast] Hematopoietic Agents Notice how these show notes are arranged: a list review of hematopoietic agents (that cause red blood cell production),... read more
General Principles of Toxicology Scope of Medical Toxicology: Occupational (Chemicals), Environmental (agricultural/air), Clinical (drug toxicity, accidental, intentional) Oral > Eye > Skin > Bites/Stings > Inhalation > Aspiration 90% poi... read more
NSAIDS Aspirin Salicylic Acid Indomethacin Diclofenac Sulindac Tolmetin Ibuprofen Naproxen Ketoprofen Pranoprofen Miroprofen Phenylbutazone Apazone Piroxicam Celecoxib Acetaminophen Chloroquine Gold salts Colchicine Probenecid Sulfinpyrazone Allopurinol C... read more
Azathioprine Corticosteroids Cyclosporine Tacrolimus Sirolimus Mycophenolate mofetil Polyclonal antithymocyte globulin Anti-CD3 monoclonal antibodies Azathioprine (AZA) imidazole derivative of 6-mercaptopurine blocks DNA synthesis decreases the migration ... read more
Drug Information and Nomenclature A. Drug Classification OTC drugs: Adequate directions can be written for the layman and they’re safe for the not-so-careful customer. B. Prescription Drugs Adequate directions can not be written for the layman. ... read more
Eicosanoids Arachidonic Acid Prostaglandins: PGE1, PGE2, PGF2a, PGI2 Thromboxane A2 Drugs NSAIDS – Aspirin, Indomethacin, Ibuprofen, Celecoxib Prostin – PGE1 Alprostadil – PGE1 Misoprostol – PGE1 derivative Dinoprostone – PGE... read more
cancer affects 1 in every 3 individuals Cancer incidence and mortality Ø Males – lung #1, prostate #2 Ø Females – lung #1, breast #2 Causes of cancer Ø most are non-inherited genetic diseases of somatic cells Ø mutations can occur ... read more
Agents that intercalate DNA Doxorubicin (Adriamycin) Daunorubicin (Daunomycin) Dactinomycin Plicamycin (Mithramycin) Agents that fragment DNA Bleomycins Agents that inhibit Topoisomerase II Etoposide (VP-16) Teniposide Amsacrine Agents that inhibit Microt... read more
1. Antifolates 2. Methotrexate (MTX) 3. Pyrimidine Analogs 4. Cytosine Arabinoside – (araC, cytarabine) 5. Fluorouracil (5-FU) 6. Purine Analogs 7. Mercaptopurine (MP) 8. Thiog... read more
Nitrogen Mustards Mechlorethamine Cyclophosphamide Melphalan Chlorambucil Nitrosureas Carmustine (BCNU) Lomustine (CCNU) Semustine Streptozocin Alkyl Sulfonates Busulfan MISC Cisplatin Procarbazine Dacarbazine Mitomycin Nitrogen Mustards – Mechloret... read more