Anatomy of the Lymphatic System

LYMPHATICS

OBJECTIVES

§  Describe the major structures of the lymphatic system and the roles that it plays in disease fighting and the distribution of metabolic products.

§  Describe the anatomical relationship to the venous system, and the physiological relationship to the portions of the nervous system mediating the stress response.

§  Describe the major nodal sites in the head and neck.

§  Be able to predict the lymphatic drainage of major head and neck regions. Know what is special about the tongue

Components of the Lymphatic System

§  The lymphatic system, as part of the circulatory system, starts with its capillaries, which begin blindly in tissue spaces.

§  The lymphatic system is closely aligned to the venous system

§  ultimately, the lymph is returned to the venous system at the base of the neck.

§  The lymphatic system contains specialized collections of tissue, including the spleen, thymus, tonsils, and nodes.

Pericervical Collar

§  This is a collection of nodal points that receive lymphatic drainage from more superior regions of the face and scalp.

§  The groups making up this ring are typically:

(1) occipital, (2) posterior auricular, (3) parotid, (4) buccal, (5) submandibular, and (6) submental.

Cervical Organization

§  Superficial cervical nodes lay along the external jugular vein,

§  whereas the deep cervical nodes lay along the internal jugular vein.

§  There are two prominent collections of named nodes that are important: (1) jugulodigastric and (2) juguloomohyoid.

§  These are so-named because they generally are located at the intersection of these muscles and the internal jugular vein.

§  In addition to these, there is a collection of pretracheal and retroharyngeal nodes

§  The deep cervical nodes are often further subdivided into superior deep and inferior deep groups.

§  The jugulodigastric and juguloomohyoid are part of the superior deep group.

§  The inferior deep group are those that are found along the subclavian vessels and are of considerable clinical significance.

Draining Principals

§  The routing of lymph is generally straightforward.

§  By-in-large, lymph drainage follows the ‘down & in’ principal.

§  superior regions drain inferiorly, and superficial regions drain deep.

§  Of course, by the nature of the lymphatic network, there is much potential variation.

§  But, this is also one of the reasons that cancer, once within the lymphatic system, can be disseminated so widely.

§  In any event, lymph collected from all parts of the body enters the venuous system in the root of the neck.

§  For example, the right lymphatic duct empties at the junction of the right subclavian and internal jugular veins.

§  The thoracic duct enters the neck slightly off of the midline behind esophagus to join at the junction of the left subclavian and internal jugular veins.

Supraclavicular (or sentinel nodes)

§  A very important clinical point is that the inferior deep group of nodes, which includes the supraclavicular collection of nodes, receive drainage from the vast majority of body regions.

§  These nodes set in the final common pathway of lymphatic drainage from the entire body.

§  For instance, cancer arising from the breast or pelvic region may present in these nodes.

§  Therefore, inspection of these nodes is important in any comprehensive assessment.

§  These nodes are not typically palpable.

Clinical Correlates

The drainage from the tongue

§  deserves special mention because of the frequency that this structure in involved in cancerous conditions.

§  The anterior two-thirds of the tongue typically drains into submental nodes and submandibular nodes, but may also bypass these pericervical nodes to drain directly in the deep cervical nodes.

§  The posterior one-third of tongue join the deep cervical nodes directly.

§  Furthermore, drainage from the central portions of the tongue may drain bilaterally, and is especially the case for the tip of the tongue.

§  This fact can make managing the spread of cancer particularly devastating, as essentially the entire neck can be involved.

Another important drainage pattern to know is from the larynx

§  Its lymphatic drainage follows the venous drainage;

§  hence, drains both superiorly and inferiorly.

§  From there, lymph drains into the deep cervical set of nodes.

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