Marijuana

Names given to Cannibus:

  • Grass
  • Pot
  • Mary jane
  • Tea
  • Weed
  • Cannibus Indica
  • Cannibus Indica – marijuana christmas tree
  • Cannibus Americana

The following Indian names were given to different preparations from cannibus:

  • Bhang comes from cut tops and low resin content
  • Ganja obtained from flowering tops and leaves and has higher quality and quantity or resin than Bhang
  • Charas obtained from top of mature plants. It is refined resin that is called Hashish

Derivatives of Cannibis:

  • Many dervatives of cannabinol have been prepared
  • The active constituents of hashish are various isomers of tetrahydrocannabinol
  • The most important is Delta-9-tetrahydrocannabinol (THC)

General Use:

  • Marijuana is second only to alcohol as the most widely used of the drugs we are including this chapter
  • Marijuana smoking is the frequent form illicit drug use in the USA
  • The drug can be ingested through:

- Smoking

- Eating

- Drinking – in the form of tea

- Intravenous injection (rare)

  • When smoked intoxication occurs almost immediately; peak plasma level within 10-30 minutes; intoxication lasts 2-4 hours
  • When the plant is eaten, a greater percentage of the drug is absorbed and the result longer (5-12 hours), but less predictable intoxication
  • Half-life may be 7 days; MOA is not well understood

Cannibus Intoxication

  • Euphoria
  • Anxiety
  • Suspiciousness or paranoid ideation
  • Sensation of slowed time
  • Impaired judgement
  • Impaired color discrimination
  • Social withdrawal
  • Inappropriate laughter
  • Dysphoric affect (at times)
  • Conjunctival injection
  • Tachycardia
  • Dry mouth
  • Increased appetite- possibility on the future treatment of annorexia nervosa
  • Depersonalization and derealization
  • Hallucinations (usually with high doses)
  • Heightened sensitivity to external stimuli (colors seem brighter, subjectively enhances the appreciation of music)
  • Splitting of consciousness
  • Synthesias- should not be used by people with seizures
  • Deeper sense of awareness
  • Sedation
  • Problems with short-term memory
  • Sometimes confusion, disorientation, and panic attacks
  • Fine shakes and tremors
  • Slight increase in body temperature, muscle strength, and motor coordination
  • Headaches, nystagmus, and mildly lowered blood pressure
  • TCH may ppt seizures in epileptics