Medication Doses: Dosage of common prescriptions

 

COMMONLY USED MEDICATIONS AND DOSAGES

 

Analgesics/Anti-inflammatory/Anti-pyretic agents

Acetaminophen (Tylenol) 650 mg po q4-6h prn fever, pain

(NB: not anti-inflammatory)

Ibuprofen (Advil, Motrin) 200-800 mg po qid

 

Antimicrobials

Against Gram-positives:

Ampicillin 1-2g IM/IV q4-6h or 250-500 mg po qid

Amoxicillin clavulanate (Augmentin) 250-500 mg po tid

(broad-spectrum – many Gram-negatives, too!)

Erythromycin ethyl succinate (EES) 400 mg po qid

Ampicillin-sulbactam (Unasyn) 1.5-3 mg IV q6h (broadspectrum

- many Gram-negatives, too!)

Vancomycin 500 mg IV q6h or 1g IV q12h (powerful initial

broad-spectrum against Gram-positives, but be sure to change

to a narrower-spectrum antibiotic as soon as culture &

sensitivity results are available! Be sure to ask your resident

before using this drug first! Beware of vanc-resistant

enterococci, an unfortunate consequence of overuse,

especially at the VA!)

Against Gram-negatives:

Ceftazidime (Fortaz) 1-2g IV q8-12h (very good broadspectrum

against Gram-negatives)

Gentamicin 1 mg/kg IV q8h. Be sure to check peak/trough

with 3rd dose (normal peak is 5-10 mcg/ml, normal trough is

<2 mcg/ml)

Against anaerobes:

Clindamycin (Cleocin) 600-900 mg IV q8h

Imipenem-cilastatin (Primaxin) 250-1000 mg IV/IM q6-8h

Metronidazole (Flagyl) 500 mg po tid

Empiric therapy for bacterial meningitis:

Ceftriaxone (Rocephin) 1-2g IV q24h

Cefotaxime (Claforan) 1-2g IV q6-8h

Empiric therapy for UTIs:

Ciprofloxacin (Cipro) 250-750 mg po bid or 200-400 mg IV

q12h

Trimethoprim/sulfamethoxazole (TMP/SMX, Bactrim) DS

(double-strength) one tablet po bid

Ofloxacin (Floxin) 200-400 mg IV/po q12h

Against TB:

Isoniazid (INH) 300 mg po qd. Be sure to supplement with

pyridoxine (B6) 25-50 mg po qd

Rifampin 600 mg po/IV qd

Pyrazinamide 15-30 mg/kg up to 2000 mg po qd

Ethambutol 15-25 mg/kg up to 2500 mg po qd

Against HIV:

Zidovudine (AZT) 200 mg po tid

Lamivudine (3TC) 150 mg po bid

Saquinavir (Invirase) 600 mg po tid

(PCP prophylaxis for CD4 < 200: Bactrim DS one po q

M,W,F)

 

Antihypertensives

Metoprolol (Lopressor) start 50 mg po bid, max 450 mg/day

Amlodipine (Norvasc) start 2.5-5 mg po qd, max 10 qd

Clonidine (Catapres) start 0.1 mg po bid, max 2.4 mg/day

Captopril (Capoten) start 25 mg po bid/tid, max 450 mg/day

 

Gastrointestinal

Famotidine (Pepcid) 20 mg IV q12h or 20-40 mg po qhs

Nizatidine (Axid) 150-300 mg po qhs

Omeprazole (Prilosec) 20 mg po qd for duodenal ulcer or

erosive esophagitis; 40 qd for gastric ulcer

Metoclopramide (Reglan) 10-30 mg po qid, 30 min before

meals and qhs

Promethazine (Phenergan) 25-50 mg po/IM/PR q4-6h prn

Nausea

 

Anticoagulants/Anti-platelet Agents

Aspirin, enteric-coated (ECASA) 325 mg po qd

Heparin load 80 units/kg IV, then mix infusion 25,000 units in

250 ml D5W (100 units/ml) and start at 18 units/kg/hr. Titrate

to APTT 2-3x normal. DVT prohylaxis: 5000 units SC q8-

12h.

Warfarin (Coumadin) load 10 mg po qd for 2-4 days, then

adjust daily dosage to APTT 2-3x normal.

 

Pulmonary

Albuterol (Ventolin) NMT (nebulizer mask treatment) 0.5 cc

in 2.5 cc NS q4-6h

Ipratropium bromide (Atrovent) MDI (metered-dose inhaler)

2-3 puffs qid

Salmeterol (Serevent) 2 puffs bid (regularly, not prn)

PRN Meds (very handy info – the Medicine float will love

you if you get these in the admission orders!)

Tylenol 650 mg po q4-6h prn T>101.5 or HA

Benadryl 25 mg po qhs prn insomnia

Maalox 30 cc po q4h prn indigestion/dyspepsia

MOM 30 cc po q4h prn constipation

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